BACKGROUND: ATP-dependent D-alanine:D-alanine ligase (Ddl) is a part of biochemical machinery involved in peptidoglycan biosynthesis, as it catalyzes the formation of the terminal D-ala-D-ala dipeptide of the peptidoglycan precursor UDPMurNAc-pentapeptide.Inhibition of Ddl prevents bacterial growth, which makes this enzyme an attractive and viable
Potential role of CSF cytokine profiles in discriminating infectious from non-infectious CNS disorders.
Current laboratory testing of cerebrospinal fluid (CSF) does not consistently discriminate between different central nervous system (CNS) disease states.Rapidly distinguishing CNS infections from other brain and spinal cord disorders that share a similar clinical presentation is critical.New approaches focusing on aspects of disease biology, such a
The Impact of Precipitation Deficit and Urbanization on Variations in Water Storage in the Beijing-Tianjin-Hebei Urban Agglomeration
Depletion of water resources has threatened water security in the Beijing-Tianjin-Hebei urban agglomeration, China.However, the relative importance of precipitation and urbanization to water storage change has not been sufficiently studied.In this study, both terrestrial water storage (TWS) and groundwater storage (GWS) change in Jing-Jin-Ji from 1
Interaction Effects of Religiosity Level on the Relationship between Religion and Willingness to Donate Organs
This study aims to investigate the interaction effect of religiosity level on the relationship between religion and willingness to donate organs.Prior studies have suggested that a high level of religiosity indicates a high level of willingness to donate organs.However, these previous works ignore the interaction effect of the level of religiosity